Surgical treatment of uterine sarcoma is the main treatment. Although the prospective study has not yet sure adjuvant chemotherapy and radiotherapy, but because of uterine sarcoma recurrence rate , most scholars still stand for Adjuvant chemotherapy or radiotherapy. Gynecologic Oncology Cooperative Group non-randomized studies have shown that embryos in the uterus of the mixed tumor Ⅰ, Ⅱ patients after pelvic radiotherapy, radiotherapy can significantly reduce the recurrence area, but no significant change in survival rates.
Another non-randomized study showed that mixed mullerian cancer of the cavity after in vitro exposure to radiation and to improve patient survival and reduce local failure rate. Radiotherapy for endometrial stromal sarcoma effective, Peters non-randomized controlled study results showed that the cisplatin and adriamycin a joint programme of effective chemotherapy. GOG Phase Ⅱ clinical trial results showed that uterine sarcoma stage Ⅲ with ifosfamide chemotherapy efficient: embryo in the uterus for 32.2 percent of the sarcoma, endometrial stromal sarcoma 33%, 17.2% of leiomyosarcoma. GOG randomized controlled study of ifosfamide, or plus cisplatin can be used as the chemotherapy treatment of the embryo in the uterus and mixed tumor recurrence in patients with advanced on the first line of chemotherapy drugs. High-dose progesterone for cell differentiation between the good quality of uterine sarcoma have a certain effect.
