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July 25, 1978, the world's first test-tube baby was born in the United Kingdom.Doctors used methods are: his wife, the body removed from the mature egg, sperm can improve on the combination with the culture medium will be injected her husband sperm, and they combine and split into eight cells and then transplanted into fertilized wife womb.This is the first generation test-tube baby technology.

China's first test-tube baby was born in 1988, is also used for the first generation of female test-tube baby technology.Thereafter, in order to address the second generation of male infertility test-tube baby technology has begun to implement, it is the exact name of "artificial insemination by donor sperm injection."Because a human egg cell, must be -10 10,000 50,000 sperm surrounding environment in order to insemination, sperm are small or weak activity of the men, because he can not provide such a good environment to do his father's lost opportunity."Second-generation test-tube baby" is a very fine needle with her husband's sperm will be "injected" into the wife's egg, the fertilized egg after the formation of replantation in the uterus to return to his wife.

Third-generation test-tube baby is a genetic disease for those who design the husband and wife is a fertilized egg to undergo a genetic examination of genetics, genetic disease genes did not choose the fertilized egg implanted in the uterus.The technology helped the couple has a genetic history of the role of healthy future generations.

In infertile couples in China, at least one million men suffering from azoospermia, a simple test-tube baby technology can help them complete the "bricks without straw", to use the sperm of other people.Sperm bank is to azoospermia, oligospermia, azoospermia weak, such as infertility and abnormal sperm and his wife established.

Stringent conditions than sperm donation.Include: age 22-45 years old, 1.70 meters tall or more, post-secondary education and above.Body symmetry,, non-genetic medical history and family history of genetic disease.Not long-term exposure to radiation, toxic and harmful substances, no drugs, alcohol, tobacco and other bad habits and serious systemic diseases, infectious diseases ... ....In order to enhance the quality of the sperm bank, sperm inventory of volunteers but also sperm motility, chromosome examination and microbiological examination to future generations will be fertilized to minimize the risk of hereditary, after layers of screening, the final pass rate is about 30%.Finally, semen preserved in liquid nitrogen at minus 196 degrees Celsius tank.In order to avoid HIV, all in the preservation of semen after six months to use after passing inspection.