A large-scale clinical trial, triple the combined therapy in patients with advanced stomach cancer survival rate doubled. Researchers in the United States held this week radiotherapy and cancer treatment Association General Assembly on the report, the United States on the clinical treatment of change.
The real treatment for stomach cancer and cardiac patients at high risk of tumor removal in the target area after receiving radiotherapy and 5 - Asia folic acid and 5-fluorouracil chemotherapy. A multi-centre study group of 603 cases of patients with 3-year follow-up found that surgery alone group disease-free survival rates of 22%, and comprehensive treatment group Biaosheng Zhi 42 percent.
As head of research, University of Kansas professor of radiation oncology clinical Dr. Steven R. Smalley said, in the U.S. this has become a standard programme. With the improvement of treatment, the prognosis of patients with significantly improved.
The treatment stems from the Minnesota Department of Mayo Hospital Oncology Dr. Leonard L. Gunderson 30 years ago the research work. He said, From the beginning of residents actually do, I recalled the simple post-operative patients with recurrent patterns, but also with a unique mode of recurrence after surgery in patients with secondary information. Although the only cure patients 1-2, but That can be good to show that the tumor recurrence site, and radiotherapy can be recurrent area.
The researchers found that sites are mainly located in the gastric recurrence, lymph nodes and lymphatic vessels to the lymph nodes. Then they will be in large-scale clinical trials in developing a complete and accurate radiation treatment planning programme submitted to Dr. Smalley. After treatment, Smalley Dr. said, 35 percent of patients with the treatment in the first case a larger or smaller deviation. But most can be corrected, thus only 6 percent of patients show greater deviation . Occurrence of the phenomenon of the mechanism is unclear. In the training of radiation oncology doctors have a lot of work to be done, though we also easy to start an error, but then usually able to complete the outstanding work.
Dr. Smalley said, gastric cancer is the world's second-cancer mortality. As conventional treatment requires only the tumor radiotherapy equipment and less expensive chemotherapy drugs, and he expected the treatment will save thousands of patients each year of life. But Gunderson said that the European surgeons believe that the expensive surgery rather than radiation, they have not yet accepted the cheap therapy. They believe that the therapy unsuitable for advanced gastric cancer. But Gunderson said that only through surgery is not enough, patients need treatment.
However unacceptable that the statistical analysis of the therapy can improve survival rates even though, but only a little over half of the integrated treatment of patients with markedly effective. Dr. Smalley said, the therapy of patients with local recurrence of an effective, but there are distant metastasis will expire. Therefore, we need to improve chemotherapy to combat the liver, lung or abdominal metastases. We have found tumor recurrence of the most vulnerable regions, and The use of the past will never used by the chemotherapy.
