Health-C0.5ml /, qod, analysis of its effects. The results of 3 to 12 in future all cured. Conclusion filamentous keratopathy, and corneal
Paper basement membrane collagen tissue degeneration, and the vitamin C on the formation of collagen fibers have a certain role, can promote the healing of cornea diseases and the treatment of corneal filamentous
Lesions.
Since June 1993 to December 1999, we have adopted subconjunctival injection of vitamin C treatment of 31 patients filamentous corneal diseases, including two cases of in-patients , 29 cases of out-patients , both Achieved good results, are summarized below.
Clinical data
1. General information: The patients were 31 cases , M 18 , M 13 ; right eye 21, left 12; aged 25 to 68 years old, an average of 52 - Year-old. Volume corneal wire: cornea has a number of large and small volumes of silk, silk vol ≤ 5a total of 4, 6 to 10 of 21, 10 a total of eight. Accompanied by eye disease: the virus keratitis seven cases, six cases of chronic conjunctivitis, Kok xerophthalmia 4 , two cases of injury, Jianyuan Yan two cases, cataract surgery after one case of retinal reattachment After one case of unknown reasons, seven cases .
2. Treatments: Ma under the table with saline Mianbang remove small volumes of filamentous, if not removed, can be used in microsurgery without teeth forceps slit lamp to remove the forceps. According to eye with the situation, local drops with antibiotics or antiviral eye drops, eye drops corneal Ning, Gao Jie-eye ointment. Subconjunctival injection of 2% lidocaine 0.3 ml + Vitamin C0.5ml , the next day, the 1st, oral multi-vitamin.
Results
1. Efficacy standards: ① cure: disappearance of filamentous, corneal smooth, fluorescence staining negative, foreign body sensation disappeared. ② effective: reduction of filamentous, fluorescence staining area reduction, to reduce symptoms. ③ invalid: filamentous of increased or unchanged, without reducing symptoms.
2. Results: 1 to 4 days effective, with an average 2.2 days; three to 12 days after all cured, an average of 7.2 days. One of them were cured after six days because of flu and relapse, and then vitamin C0.5ml subconjunctival injection a day, four days later, fully healed, and the remaining six to seven annual follow-up without recurrence.
Discussion
Filamentous keratopathy is a corneal surface size of the epithelial volumes for the characteristics of a silk corneal diseases. Main symptoms of a foreign body sensation, who have significantly heavier the eye pain, photophobia, tears and other symptoms. Corneal visible on the size of the volumes wire, such as needle or sesame, transparent or translucent, with curly epithelial spring-like, attached to one end of corneal epithelial spalling, the other end ofcorneal epithelial surface. There is also a loss of epithelial is curled into corporations, such as nodular corneal higher plane. Some people think that with the corneal epithelial some unhealthy factors or unusual movement of the eyelid Kai-related, occurred in the virus keratitis, Kok xerophthalmia, absolutely
Of glaucoma, corneal damage, wear contact lenses and eye surgery after the long-term package of patients. Also reported occurred in PRK, and some not accompanied by other eye and independent existence. Because of its complex causes, treatment of a variety of methods, evaluation and treatment also mixed. The occurrence of the disease is limited to corneal epithelium of the cornea has yet to see a deep violations of the report. Corneal epithelium of the solid ingredients, in addition to contain nucleic acid, protein, fat, carbohydrate, ATP, but also contains Vitamin C, which corneal epithelium vitamin C more concrete floors. Corneal collagen synthesis process, fibroblasts intake of lysine and proline, collagen synthesis and peptide chain, and the proline and lysine hydroxylation process must be involved in vitamin C. Vitamin C to participate in the formation of collagen fibers, and the healing of the wounds. Now that the volume of silk and epithelial basement membrane collagen degeneration of the organization, its main lesions only in the deep on the bottom of Piji, healing after leaving muddy. Therefore, vitamin C for the treatment of filamentous corneal diseases, can promote the healing of corneal diseases.
We have since 1993, the more obvious symptoms of disease or corneal diseases of the filament, in addition to treatment with eye disease, given subconjunctival injection of vitamin C treatment, condition quickly improved, the final were cured. At the same time one of them patients have hypertension, high blood lipid disease, cerebrovascular accident aftermath, the drying of the cornea, has used BFGF, CAT, ACV eyes water, Gao Jie-treatment and closed eye ointment, Xia Lei, four weeks after treatment, Results are still poor. We have to subconjunctival injection of vitamin C0.25ml / times, the day after injection, reducing the beginning of filamentous, the seventh day of corneal epithelial fully transparent, all the volumes of filamentous disappeared. This group of vitamin C subconjunctival injection for one to four days after the onset, 3 to 12 days all cured. The drug cheap and simple method of administration, and avoid direct Diyao stimulate the cornea caused symptoms, received better treatment. We believe that filamentous keratopathy Piji and on the bottom of the collagen tissue degeneration, vitamin C on the formation of collagen fibers have a certain role, can promote the healing of corneal diseases, to be effective in the treatment of filamentous corneal diseases.
